منابع مشابه
The sodium pump needs its 1 subunit
The sodium pump Na,K-ATPase, located in the plasma membrane of all animal cells, is a member of a family of ion-translocating ATPases that share highly homologous catalytic subunits. In this family, only Na,K-ATPase has been established to be a heterodimer of catalytic (a) and glycoprotein (/3) subunits. The /3 subunit has not been associated with the pump’s transport or enzymatic activity, and...
متن کاملGyrification from constrained cortical expansion.
The exterior of the mammalian brain--the cerebral cortex--has a conserved layered structure whose thickness varies little across species. However, selection pressures over evolutionary time scales have led to cortices that have a large surface area to volume ratio in some organisms, with the result that the brain is strongly convoluted into sulci and gyri. Here we show that the gyrification can...
متن کاملDecreased gyrification in major depressive disorder.
Structural and functional abnormalities have been extensively reported in major depressive disorder, but possible changes in cortical folding have not yet been explored in this disorder. This study investigated this issue in major depressive disorder using the local gyrification index. High-resolution magnetic resonance imaging was performed in 18 patients with first-episode major depressive di...
متن کاملCortical Gyrification Patterns Associated with Trait Anxiety
Dispositional anxiety is a stable personality trait that is a key risk factor for internalizing disorders, and understanding the neural correlates of trait anxiety may help us better understand the development of these disorders. Abnormal cortical folding is thought to reflect differences in cortical connectivity occurring during brain development. Therefore, assessing gyrification may advance ...
متن کاملSodium Flux in Necturus Proximal Tubule under Voltage Clamp
Na transport and electrical properties of Necturus renal proximal tubules were analyzed, in vivo, by a voltage clamp method which utilizes an axial electrode in the tubule lumen for passage of current and simultaneous determination of net fluid (or Na) flux by the split droplet method. When the average spontaneous transepithelial potential difference of -8 mv (lumen negative) was reduced to zer...
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ژورنال
عنوان ژورنال: Neuron
سال: 2018
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2018.08.005